PAX5 [6A1]

Catalog Number：OM638990

  • Fig1: Western blot analysis on (A) Ramos, (B) human tonsil, and (C) Daudi lysates using anti-PAX5.

  • Fig2： Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PAX5.

Product Profile

Product Name PAX5 [6A1]
Antibody Type Primary Antibodies
Product description 
The human paired box protein Pax-5 (PAX5) is a member of the paired box domain family of transcription factors that play a role in B-cell differentiation, neural development, and spermatogenesis (1). As a result, its expression is detected in the developing central nervous system (CNS) and testis (1). In particular, PAX5 is essential for maintaining the identity and function of mature B cells during late B lymphopoiesis (2). PAX5 is a B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation (3). During B-cell differentiation, PAX5 interacts with DAXX, a bridge protein that helps PAX5 to function as both a transcriptional activator and a repressor (4). A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia (1).
Immunogen 
peptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBICCIHCFC
WB:1:1,000
ICC:1:100
IHC:1:100
FC:1:10-100
Species Reactivity

HumanMouse
Concentration 1 mg/mL.

Target Information

Alternative Names
B cell lineage specific activator antibody B cell lineage specific activator protein antibody B cell specific activator protein antibody B cell specific transcription factor antibody B-cell-specific transcription factor antibody BSAP antibody EBB-1 antibody KLP antibody Paired box 5 antibody Paired box gene 5 (B cell lineage specific activator protein) antibody Paired box gene 5 (B cell lineage specific activator) antibody Paired box gene 5 antibody Paired box homeotic gene 5 antibody Paired box protein Pax 5 antibody Paired box protein Pax-5 antibody Paired domain gene 5 antibody PAX 5 antibody PAX5 antibody PAX5_HUMAN antibody Transcription factor PAX 5 antibody
Molecular Weight(MW) 45kDa
Cellular Localization Nucleus

Database Links

SwissProt ID Q02548

Application

  • Application

    Fig1: Western blot analysis on (A) Ramos, (B) human tonsil, and (C) Daudi lysates using anti-PAX5.

  • Application

    Fig2： Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PAX5.

Positive Control Ramos, human tonsil tissue.
Application Notes
WB:1:1,000
ICC:1:100
IHC:1:100
FC:1:10-100

Additional Information

Form Liquid
Storage Instructions Store at -20 ℃. Stable for 12 months from date of receipt
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM638990
  • Price: $336.00
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